Fulminant hepatic failure after intravenous injection of sublingual buprenorphine in a patient with hepatitis C

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Fulminant hepatic failure after intravenous injection of sublingual buprenorphine in a patient with hepatitis C

A 20-year-old indigenous Australian male was admitted to the intensive care unit with fulminant hepatic failure secondary to intravenous use of buprenorphine, which had been prescribed sublingually for opioid dependence. Intravenous buprenorphine-induced hepatitis is well recognized, however, life-threatening fulminant hepatic failure has not previously been reported.

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Fulminant hepatic failure (FHF) due to acute hepatitis C

Acute hepatitis C (HCV) infection has been identified as an important cause of fulminant hepatic failure (FHF), characterized by rapid deterioration of liver function from massive hepatic necrosis leading to encephalopathy and multi-organ failure. We admitted a female patient at Shalamar Hospital with jaundice, fever, encephalopathy and coagulopathy of short duration with no history of any como...

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ژورنال

عنوان ژورنال: Clinical Case Reports

سال: 2015

ISSN: 2050-0904,2050-0904

DOI: 10.1002/ccr3.314